Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Kieran James Lennon0
Benedikt Steitz0
Katja Maren Fastnacht0
Bernd Harald Liepold0
Claudia Bettina Packhaeuser0
Julie Kay Cahill0
Michael Karl Bechtold0
Date of Patent
May 7, 2024
0Patent Application Number
183123330
Date Filed
May 4, 2023
0Patent Citations
...
Patent Primary Examiner
Patent abstract
The present invention relates to a pharmaceutical formulation comprising the drug 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one in a solid dispersion with a matrix polymer that exhibits low hygroscopicity and high softening temperature, such as copovidone. The invention also relates to a daily pharmaceutical dose of the drug provided by such a formulation. In addition, the invention relates to the use of a matrix polymer that exhibits low hygroscopicity and high softening temperature in solid dispersion with 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one for increasing the bioavailability of the drug.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.